Quick Checkout

By clicking Buy Now, you agree to our TOS and Privacy Policy.

Available Games
Available Games

PoE Poisonous Concoction Pathfinder Guide

Path of Exile is the most played ARPG and consist of many different build based on other exiles suiting many different playstyles. The Pathfinder build, known as Poisonous Concoction, is a versatile choice for starting a new league in which enemies can be heavily damaged by hurling poisonous flasks. The build's sturdy defensive capabilities enable it to withstand most enemy attacks. As a result, it is an excellent option for novice players looking to learn and experiment with the game, as it does not necessitate any unique equipment and is straightforward to equip. So, for an overview of the Poisonous Concoction, break down its skills and gem linking and how it can help you earn fast PoE currency


PoE Poisonous Concoction Pathfinder Guide pic


A Brief Introduction to Poisonous Concoction

Poisonous Concoction is a newly added attack skill based on poison damage in Path of Exile's 3.16 Scourge League. It boasts exceptional clearing capabilities and a unique method of scaling damage, making it a formidable force in the game. This build is perfect for players who want to progress through the game without breaking the bank and want a build that can be maximized with a reasonable amount of currency, yielding incredible results.


Build Mechanics

This particular build in Path of Exile utilizes the Pathfinder ascendancy class and the potent Poisonous Concoction skill to achieve exceptional defensive scaling. Using Poisonous Concoction, which deals heavy poison damage, the build can inflict significant damage on enemies while also providing great survivability through stacking various defensive mechanisms such as armor, evasion, suppression, life, and elemental damage reduction.


In the endgame version, the build achieves unparalleled durability, allowing it to withstand even the most challenging encounters easily. This is accomplished while maintaining millions of DPS for boss fights, which makes the build a formidable force in the game. Additionally, the build offers above-average clear speed, making it an excellent choice for players looking to progress through the game efficiently.


Overall, this build is an excellent option for players looking for a high-performing, durable, and versatile build that offers powerful offensive and defensive capabilities.


PoE Poisonous Concoction Pathfinder Guide Mechanics


Poisonous Concoction Pathfinder – Gameplay

Playing this build is similar to a standard ranged character, except that instead of using a bow to fire projectiles, you use acidic flasks to throw at enemies, inflicting potent Poison/DoT effects on impact. In contrast to projectiles, flasks do not deal damage in mid-air or hit enemies, meaning that skills like Pierce/Chain or Fork will not be helpful. This unique playstyle resembles that of a grenadier, a new concept in Path of Exile.


In addition to excellent mobility, this build offers solid single-target DPS and good clear speed, typical of Ranger characters. Pathfinder's Ascendancy and multiple defensive mechanics make it possible to engage in close combat with monster packs and face-end game bosses and quickly progress through content. Overall, this well-balanced build is highly enjoyable and suitable for players looking for a unique playstyle while maintaining solid performance in combat.


Leveling Up your Build

Leveling up with Poison/Ranger is easy. However, it's not advised to do so using Poisonous Concoctions. You cannot sustain enough Life Flask charges to benefit from the extra damage added. You will need more extra Projectiles, initially making this build feel very weak. A Claw and Cobra Lash is recommended, offering decent DPS and extra chain, allowing you to level up your character quicker. After gaining Greater Projectile Support Gem, you can use Concoction in act 4. Below are some basic leveling Skill Gem setups and several useful Uniques for this build.



Skills Breakdown of Poisonous Concoction

Here is a skill breakdown of the Poisonous Concoction build


1.   Poisonous Concoction

Poisonous Concoction is a throwing skill that poisons enemies upon impact. When you use this skill, it consumes two available Life Flask charges and deals extra damage based on a percentage of the life that the Life Flask would have restored. Consequently, crafting flasks is a valuable investment, much like crafting weapons in other builds.


2.   Plague Bearer

Plague Bearer is an ability that stores a portion of the Poison Damage inflicted by the player. Once fully charged, it can be triggered to unleash a Poisonous Aura, annihilating every enemy within its range.


3.   Wither Totem

This totem applies the Wither spell to enemies, causing them to suffer a debuff that reduces their movement speed and increases their vulnerability to Chaos Damage."


4.   Shield Charge

Shield Charge is a skill that helps us move quickly through the game. With this skill, you can charge forward using your shield. The faster you can move and attack, the faster you'll be able to charge ahead with Shield Charge.


Poisonous Concoction Pathfinder shield charge


Ascendancy Breakdown of Build

The Pathfinder is a character built in Path of Exile that specializes in enhancing flasks and poison damage. Additionally, it provides a valuable form of life recovery. This means the character can survive longer and deal more damage, thanks to the Pathfinder's unique abilities. By investing in Pathfinder's skill tree, you can create a powerful and versatile character capable of handling various situations. The Pathfinder is an excellent choice for players who want to take advantage of flasks and poison-based attacks while staying alive in combat.


1.   Nature's Reprisal

Nature's Reprisal is a skill that boosts damage output and provides a wider range of attacks. It can be a valuable asset in combat, helping you take down enemies more efficiently. This is especially helpful when facing multiple foes, as the increased area of effect allows you to hit more targets at once. The skill is designed to give you an edge in battle and enhance your effectiveness in combat situations. With Nature's Reprisal, you can increase your damage and coverage, making it easier to take on even the most formidable foes.


2.   Master Toxicist

With the Master Toxicist passive, you will gain a damage boost and the ability to spread poison to nearby enemies whenever an enemy is defeated.


3.   Nature's Adrenaline 

Nature's Adrenaline allows us to move and attack faster, but its true benefit is that it enables us to withstand and survive lethal damage.



Key Build Information - Poisonous Concoction

Here is critical build information about the build


Poisonous Concoction's Life Flask Scaling

Using Poisonous Concoction to attack will consume two charges from your Life Flask, if available. As a result, you will deal additional damage equivalent to a percentage of the life you would have regained if you had consumed that particular Life Flask. As a result, the only relevant attribute for your Life Flask is the Increased Life recovery stat. The perfect Life Flask for this purpose will be a Saturated Divine Life Flask of the Cure.


The Quality of your Life Flask is critical, as it can significantly impact the outcome. You can use Glassblower's Baubles to improve the quality of your life Flask up to 20%. To counter the depletion of Flask charges, you can utilize Replenishing Remedies.


Automating your Flasks for instant Life Recovery

To enhance your build, it is advisable to incorporate Master Surgeon, which replenishes 6% of your life when you utilize a Flask. You can automate this Life Recovery process with the following steps:


Acquire three Utility Flasks, namely Granite Flask, Jade Flask, and Quicksilver Flask, with the Flagellant's Prefix. This prefix provides you with Gain 3 Charges whenever an enemy hits you. Then, apply the Used when Charges Reach Full enchantment on each flask.


This mechanism ensures that when you are hit, your Flasks refill automatically and instantly activate when they become full, allowing you to recover 6% of your Life from Master Surgeon. To enhance consistency, you can increase the Flask Charges Gained by at least 33% on your Passive Tree to scale the three charges per hit to four.




In this article, we have briefly explained the Poisonous Concoction Pathfinder. We have broken down the build to make it easy to understand. You can go through the guide to learn about the build.



Copyright © 2006-2022 MmoGah.com. All rights reserved. All trademarks referenced herein are the properties of their respective owners.